Custom Peptides
Cayman Chemical Gernylgernylaceton 10mg
An inducer of Hsp expression that increases Hsp70, Hsp22, Hsp27, Hsp90, and Hsp105 levels in various cells and tissues; orally bioavailable and has diverse effects in vivo, including hepatoprotective, neuroprotective, and antiulcerative effects
Cayman Chemical Phylnthn 10mg
A bioactive lignan component of P. amarus with antioxidative and hepatoprotective properties; scavenges DPPH radicals (IC50 = 7.4 µM) and alleviates carbon tetrachloride-induced lipid peroxidation and cytotoxicity in a human hepatoma HepG2 cell line
Cayman Chemical Maltotetraose 10mg
A tetrasaccharide; increases the α-amylase synthesis rate in B. stearothermophilus three-fold greater than sucrose or glucose when used at at 0.1 mM; inhibits the growth of E. carotovora in a cylinder-agar plate assay at 750 μg/ml; inhibits TNF-α-induced expression of ICAM-1 in MOVAS-1 mouse VSMCs
Cayman Chemical L-threo-PPMPhydrochlorIde 10mg
An inhibitor of glucosylceramide synthetase; isomer of D-threo-PPMP; inhibits the growth of MCF-7, MDA-MB-468, and SK-BR-3 breast cancer cells (ED50s = 4, 7, and 6 μM, respectively)
Cayman Chemical SynthetIcE-Ajoen 10mg
A disulfide with diverse biological activities; active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 UG/ml, respectively) and fungi (MICs = 15-50 UG/ml); inhibits proliferation of a variety of cancer cells (IC50s = 18.6-61 µM); inhibits human glutathione reductase and T. cruzi trypanothione reductase at 200 µM; neuroprotective in a gerbil model of ischemia-reperfusion injury, reducing reactive astrocytosis and microgliosis in the hippocampal CA1 region at 25 mg/kg
Cayman Chemical 4chloroaCynocInamIc AcId 10mg
A phenylpropanoid which readily co-crystallizes with various biomolecules
Cayman Chemical Periplogenin 10MG
A cardenolide and an active metabolite of periplocin with diverse biological activities; reduces the activity of porcine Na+/K+ ATPase at 0.3 or 0.6 µM; induces apoptosis in U937 and PC3 prostate cancer cells, as well as inhibits the proliferation of these cells (EC50s = 1.41 and 1.2 µM, respectively) at 0.1 or 0.2 µM; increases ROS production and induces necroptosis in HaCaT keratinocytes at 2 UG/ml; reduces EAr thickness in a mouse model of TPA-induced psoriasis
Cayman Chemical 3DeoxyDglyceroDgalacto2 10mg
A naturally occuring deaminated sialic acid that is thought to be a precursor for the biosynthesis of other members of the sialic acid family; can be used to analyze nonulosonic acid residues in polysialoglycoproteins
Cayman Chemical PfDHODH-IN-1 10mg
A DHODH inhibitor (IC50s = 190, 47, and 21 nM for the human, mouse, and rat enzymes, respectively); inhibits delayed-type hypersensitivity reactions in mice and rats at 30 and 10 mg/kg, respectively
Cayman Chemical SophocarpIn 10mg
An alkaloid with diverse biological activities; cytotoxic to various cancer cell lines (IC50s = 1.64-12.86 mM); nematocidal against B. xylophilus in vitro; reduces infarct size, cardiac muscle fiber swelling and hypertrophy, and neutrophil infiltration in a rat model of myocardial ischemia and reperfusion injury at 30 mg/kg; decreases liver weight, fibrosis, and levels of IL-6, TNF-α, and TGF-β1 in a rat model of NASH; reduces carrageenan-induced hind paw edema in rats and decreases acetic acid-induced writhing in mice at 15 and 30 mg/kg
Cayman Chemical RabeprazolesodIum salt 10mg
A proton pump inhibitor; inhibits the gastric H+/K+ ATPase (IC50 = 72 nM); activated more rapidly and over a greater pH range than other proton pump inhibitors; inhibits gastric acid secretion in pylorus-ligated rats and a rat model of gastric fistula at 30 mg/kg; inhibits the growth of several strains of H. pylori in vitro (MIC50s = 1.57-3.13 μg/mL)
Cayman Chemical Deslnosde 10mg
A cardiac glycoside; induces ventricular tachycardia in anesthetized dogs at 0.18 mg/kg
Cayman Chemical Maackan 10mg
the histamine H1 receptor in serum-starved HeLa cells at 10, 20, or 30 µM; inhibits PMA-induced increases in the levels of mRNA encoding Il-4 in RBL-2H3 cells at 50 or 150 µM; decreases LPS-induced increases in NO production in RAW 264.7 macrophages (IC50 = 27 µM); increases survival in a mouse model of CLP-induced sepsis at 2.5 or 5 mg/kg; reduces the number of sneezes and the extent of nasal redness, swelling, and watery rhinorrhea in a rat model of TDI-induced allergies at 20 mg/kg per day
Cayman Chemical 4 4-DIcynobenzhydrol 10mg
An analytical reference standard that is a metabolite of letrozole; has been used as a marker of letrozole use in athletes; intended for research and forensic applications